Nigeria, Africa’s most populous nation has become the first country in the world to roll out a new vaccine- Men5CV, to protect people against five strains of the meningococcus bacteria.
The new vaccine, which was recommended by the World Health Organization (WHO) is said to have the potential to change the trajectory of meningitis disease and prevent future outbreaks.
A statement published on WHO’s website on Friday indicates that the vaccine and emergency vaccination activities are funded by Gavi, the Vaccine Alliance, which funds the global meningitis vaccine stockpile and supports lower-income countries with routine vaccination against meningitis.
Data from WHO shows Nigeria recorded 1,742 suspected meningitis cases, including 101 confirmed cases and 153 deaths in seven states of Adamawa, Bauchi, Gombe, Jigawa, Katsina, Yobe, Zamfara, between 1 October 2023 and 11 March.
WHO said the outbreak of “Neisseria meningitidis (meningococcus) serogroup C” led to the recorded cases.
Nigeria is one of the 26 meningitis hyper-endemic countries in Africa, as the region recorded a 50 per cent jump in annual meningitis cases in 2023.
Vaccination campaign
The WHO noted that to contain the severe meningitis outbreak, a vaccination campaign was undertaken from 25 to 28 March, to initially reach more than one million people aged 1-29 years.
The WHO Director-General, Tedros Ghebreyesus said meningitis is an old and deadly foe, but the new vaccine can potentially change the trajectory of the disease, preventing future outbreaks and saving many lives.
Dr Ghebreyesus said Nigeria’s rollout brings the world one step closer to the goal of eliminating meningitis by 2030.
In his remarks, the Coordinating Minister of Health and Social Welfare, Muhammad Pate, said the vaccine provides health workers with a new tool to stop the outbreak and put the country on a path to elimination.
Mr Pate said the ministry got the support of community leaders with the rollout and is working on expansion.
“We’ve done a lot of work preparing health workers and the health system for the rollout of this new vaccine. We got invaluable support from our populations despite this fasting period and from our community leaders especially the Emir of Gumel in Jigawa State who personally launched the vaccination campaign in the state,” he said.
“We’ll be monitoring progress closely and hopefully expanding the immunization in the coming months and years to accelerate progress.”
According to the UK Minister for Development and Africa, Andrew Mitchell, the rollout of one million vaccines in northern Nigeria will help save lives, prevent long-term illness, and boost the goal of defeating meningitis globally by 2030.
“This is exactly the kind of scientific innovation, supported by the UK, which I hope is replicated in years to come to help us drive further breakthroughs, including wiping out other diseases,” he said.
New vaccine
WHO explained that the “revolutionary” new vaccine offers a powerful shield against the five major strains of the meningococcal bacteria (A, C, W, Y, and X) in a single shot.
It said all five strains cause meningitis and blood poisoning, noting that the vaccine provides broader protection than the current one used in much of Africa, which is only effective against the A strain.
“The new vaccine has the potential to significantly reduce meningitis cases and advance progress in defeating meningitis. This is especially important for countries like Nigeria where multiple serogroups are prevalent.”
It added that the new vaccine uses the same technology as the meningitis A conjugate vaccine (MenAfriVac®️), which wiped out meningococcal A epidemics in Nigeria.
The global health body also noted that the new multivalent conjugate vaccine was 13 years in the making and was based on a partnership between PATH and the Serum Institute of India, with funding support from the UK government’s Foreign, Commonwealth and Development Office (FCDO).
About meningitis
According to the Centre for Disease Control, Meningitis is an inflammation (swelling) of the protective membranes covering the brain and spinal cord.
This inflammation can be caused by infection with organisms like bacteria, viruses, parasites, or fungi but the highest global burden is seen with bacterial meningitis. Around one in six people who get this type of meningitis die and one in five have severe complications, according to the WHO.
The WHO describes meningitis as a devastating disease, which remains a
major public health challenge.